ERG Ion Channel 2 Antibody

• Background:

  ERGIon Channel2 possibly play role in transport between endoplasmic reticulum and Golgi. ERGIon Channel2 is downregulated in prostate cancer. ERGIon Channel2 may play an important role in the growth and tumorigenicity of PC-3 prostate tumor cells. Ectopic expression of a partial sequence of ERGIon Channel2 as a VP22-fusion protein in prostate cancer cell line, PC-3, induced cellular senescence. Interferon-beta (IFN-beta) and a number of IFN-inducible genes were upregulated by the ERGIon Channel2-VP22 fusion protein.

• NCBI Gene ID:

  51290

• Swiss Prot:

  Q96RQ1

• Accession Number:

  NP_057654

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ERG Ion Channel 2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ERG Ion Channel 2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  43 kDa

• Applications Notes:

  ERG Ion Channel 2 antibody can be used for detection of ERG Ion Channel 2 by ELISA at 1:62500. ERG Ion Channel 2 antibody can be used for detection of ERG Ion Channel 2 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  ERGIC2

• NCBI Official Name:

  ERGIC and golgi 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Thomas J. Nelson, et al., (2007) J Biol Chem 282:31238.

• Other Product Names:

  ERGIon Channel2, PTX1, CDA14, Erv41, cd002

• Tested Applications:

  ELISA, WB

• Protein ID:

  50959176

• Physical Properties:

  Liquid