EGR1 Antibody

• Background:

  Early Growth Response Protein 1 (EGR1, Krox-24 protein, nerve growth factor-induced protein A, Transcription factor ETR103, Zinc finger protein 225) belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.

• NCBI Gene ID:

  13653

• Swiss Prot:

  P08046

• Accession Number:

  NP_031939

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse EGR1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1282 - 3T3 (NIH) Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store EGR1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  59 kDa

• Applications Notes:

  EGR1 antibody can be used for detection of EGR1 by ELISA at 1:12500. EGR1 antibody can be used for detection of EGR1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  EGR1

• NCBI Official Name:

  Early growth response 1

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Schnell, F.J., et al., (2006) J. Immunol. 176 (8), 4740-4747.

• Other Product Names:

  EGR1, egr, TIS8, Zenk, Egr-1, NGFIA, Zfp-6, ETR103, Krox-1, Krox24, NGF1-A, NGFI-A, Zif268, Krox-24, A530045N19Rik

• Tested Applications:

  ELISA, WB

• Protein ID:

  6681285

• Physical Properties:

  Liquid