SLITRK1 Antibody

• Background:

  Members of the SLITRK family, such as SLITRK1, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins. Most SLITRKs, but not SLITRK1, also have C-terminal regions that share homology with neurotrophin receptors. SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity.Members of the SLITRK family, such as SLITRK1, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742) . Most SLITRKs, but not SLITRK1, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315) . SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]) .

• NCBI Gene ID:

  114798

• Swiss Prot:

  Q96PX8

• Accession Number:

  NP_443142

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLITRK1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Signal Transduction

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10410 - Fetal Lung Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SLITRK1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  78 kDa

• Applications Notes:

  SLITRK1 antibody can be used for detection of SLITRK1 by ELISA at 1:312500. SLITRK1 antibody can be used for detection of SLITRK1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  SLITRK1

• NCBI Official Name:

  SLIT and NTRK-like family, member 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Scharf, J.M., Neurology 70 (16 PT 2), 1495-1496 (2008) .

• Other Product Names:

  SLITRK1, KIAA0918, KIAA1910, LRRC12, RP11-395N17.1, TTM

• Tested Applications:

  ELISA, WB

• Protein ID:

  40217817

• Physical Properties:

  Liquid