RNASEL Antibody

• Background:

  This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele.

• NCBI Gene ID:

  6041

• Swiss Prot:

  Q05823

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 472-741 of human RNASEL (NP_066956.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 84kDa

• Fragment:

  IgG

• Symbol:

  RNASEL

• Positive Control 2:

  HT-29

• Positive Control 3:

  Jurkat

• NCBI Official Name:

  Ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  RNASEL, RNS4, PRCA1

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid