IL1RAPL1 Antibody

• Background:

  The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2) . This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities.

• NCBI Gene ID:

  11141

• Swiss Prot:

  Q9NZN1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 130-210 of human IL1RAPL1 (NP_055086.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  A-431

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 90kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  IL1RAPL1

• Positive Control 2:

  Mouse brain

• Positive Control 3:

  Mouse heart

• Positive Control 4:

  Rat brain

• Positive Control 5:

  Rat heart

• NCBI Official Name:

  Interleukin 1 receptor accessory protein like 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  IL-1-RAPL-1, IL-1RAPL-1, IL1R8, IL1RAPL, IL1RAPL-1, MRX1MRX21, MRX34, OPHN4, TIGIRR-2, interleukin-1 receptor accessory protein-like 1, X-linked interleukin-1 receptor accessory protein-like 1, interleukin 1 receptor-8, mental retardation, X-linked 1oligophrenin-4, three immunoglobulin domain-containing IL-1 receptor-related 2

• Tested Applications:

  WB

• Physical Properties:

  Liquid