PI3 Kinase p110 beta Antibody

• Background:

  This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K) . These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB) . PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  5291

• Swiss Prot:

  P42338

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 771-1070 of human PI3 Kinase p110 beta (NP_006210.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Immunology, Innate Immunity, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  DU145

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 122kDa

• Fragment:

  IgG

• Symbol:

  PIK3CB

• Positive Control 2:

  SW480

• Positive Control 3:

  HeLa

• Positive Control 4:

  Mouse lung

• NCBI Official Name:

  Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PIK3CB, PI3K, PIK3C1, P110BETA, PI3KBETA

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid