SARS-CoV-2 Nucleocapsid Control Antibody [4A1W0]

• Background:

  Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

• NCBI Gene ID:

  43740575

• Swiss Prot:

  P0DTC9

• Accession Number:

  #YP_009724397.2

• Reactivity:

  Virus

• Immunogen:

  HEK293 derived SARS-COV-2 Nucleocapsid, amino acids Ser2-Ala419

• Clonality:

  Recombinant Monoclonal

• Clone:

  4A1W0

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Infectious Disease, COVID-19

• Purification:

  Affinity Purified, Endotoxin Level: < 1.0 EU/ug of the protein by LAL method.

• Concentration:

  1mg/ml

• Buffer:

  Supplied as a 0.2um filtered solution in PBS, pH 7.4.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  This antibody can be stored at 2˚ C to -8˚ C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20˚ C to -80˚ C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Fragment:

  Human IgG

• Specificity:

  SARS-CoV-2

• Symbol:

  N

• NCBI Official Name:

  Nucleocapsid phosphoprotein

• NCBI Organism:

  Severe acute respiratory syndrome coronavirus 2

• Other Product Names:

  SARS-CoV-2 Nucleocapsid Protein, SARS-CoV-2 NP, nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2], novel coronavirus N Protein, novel coronavirus Nucleocapsid Protein, 2019-nCoV Nucleoprotein, 2019-nCoV N, 2019nCoV N, 2019-nCoV N Protein, 2019 peak N Protein, 2019-nCoV nucleocapsid protein.

• Tested Applications:

  ELISA

• Protein ID:

  1798174255

• Physical Properties:

  Liquid