NFAT4 (NFATC3) (NM_173165) Human Recombinant Protein

• Background:

  The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2010]

• Synonyms:

  NF-AT4c; NFAT4; NFATX

• Gene ID:

  4775

• UniProt:

  Q12968, B5B2S1

• Accession Number mRNA:

  NM_173165

• Chromosomal Location:

  16q22.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Axon guidance, B cell receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway

• Field of Research:

  Axon guidance, B cell receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  115.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  NFATC3

• Species:

  Human

• Protein ID:

  NP_775188

• Overview:

  Recombinant protein of human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 (NFATC3), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/4775

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q12968

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_173165

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_775188