CORO2A (NM_003389) Human Recombinant Protein

• Background:

  This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]

• Synonyms:

  CLIPINB; IR10; WDR2

• Gene ID:

  7464

• UniProt:

  Q92828, A0A024R150, A8K9S3

• Accession Number mRNA:

  NM_003389

• Chromosomal Location:

  9q22.33

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  59.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CORO2A

• Species:

  Human

• Protein ID:

  NP_003380

• Overview:

  Recombinant protein of human coronin, actin binding protein, 2A (CORO2A), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7464

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q92828

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003389

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003380