Josephin 1 (JOSD1) (NM_014876) Human Recombinant Protein

• Background:

  Deubiquitinates monoubiquitinated probes (in vitro) . When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell motility independently of its catalytic activity.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  DJ508I15.2

• Gene ID:

  9929

• UniProt:

  Q15040, A0A024R1P5

• Accession Number mRNA:

  NM_014876

• Chromosomal Location:

  22q13.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  23 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  JOSD1

• Species:

  Human

• Protein ID:

  NP_055691

• Overview:

  Recombinant protein of human Josephin domain containing 1 (JOSD1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9929

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q15040

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_014876

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_055691