EZH2 (NM_004456) Human Recombinant Protein

• Background:

  This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]

• Synonyms:

  ENX-1; ENX1; EZH1; EZH2b; KMT6; KMT6A; WVS; WVS2

• Gene ID:

  2146

• UniProt:

  Q15910, A0A090N8E9

• Accession Number mRNA:

  NM_004456

• Chromosomal Location:

  7q36.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Activity:

  261737102617371027869166

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  85.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  EZH2

• Species:

  Human

• Protein ID:

  NP_004447

• Overview:

  Recombinant protein of human enhancer of zeste homolog 2 (Drosophila) (EZH2), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2146

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q15910

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004456

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004447