CD36 (NM_000072) Human Recombinant Protein

• Background:

  The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]

• Synonyms:

  BDPLT10; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; SCARB3

• Gene ID:

  948

• UniProt:

  P16671, A4D1B1

• Accession Number mRNA:

  NM_000072

• Chromosomal Location:

  7q21.11

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Adipocytokine signaling pathway, ECM-receptor interaction, Hematopoietic cell lineage, PPAR signaling pathway

• Field of Research:

  Adipocytokine signaling pathway, ECM-receptor interaction, Hematopoietic cell lineage, PPAR signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transmembrane

• Molecular Weight:

  52.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CD36

• Species:

  Human

• Protein ID:

  NP_000063

• Overview:

  Recombinant protein of human CD36 molecule (thrombospondin receptor) (CD36), transcript variant 3

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/948

• Uniprot URL:

  https://www.uniprot.org/uniprot/P16671

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_000072

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_000063