LMBR1 (NM_022458) Human Recombinant Protein

• Background:

  This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. [provided by RefSeq, Jul 2008]

• Synonyms:

  ACHP; C7orf2; DIF14; LSS; PPD2; THYP; TPT; ZRS

• Gene ID:

  64327

• UniProt:

  Q8WVP7

• Accession Number mRNA:

  NM_022458

• Chromosomal Location:

  7q36.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transmembrane

• Molecular Weight:

  54.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  LMBR1

• Species:

  Human

• Protein ID:

  NP_071903

• Overview:

  Recombinant protein of human limb region 1 homolog (mouse) (LMBR1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/64327

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8WVP7

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_022458

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_071903