IGFBP4 (NM_001552) Human Recombinant Protein

• Background:

  This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008]

• Synonyms:

  BP-4; HT29-IGFBP; IBP4; IGFBP-4

• Gene ID:

  3487

• UniProt:

  P22692, A0A024R1U8

• Accession Number mRNA:

  NM_001552

• Chromosomal Location:

  17q21.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Secreted Protein

• Molecular Weight:

  25.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  IGFBP4

• Species:

  Human

• Protein ID:

  NP_001543

• Overview:

  Recombinant protein of human insulin-like growth factor binding protein 4 (IGFBP4)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/3487

• Uniprot URL:

  https://www.uniprot.org/uniprot/P22692

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001552

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001543