Acetyl CoA synthetase (ACSS2) (NM_018677) Human Recombinant Protein

• Background:

  This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]

• Synonyms:

  ACAS2; ACECS; AceCS1; ACS; ACSA; dJ1161H23.1

• Gene ID:

  55902

• UniProt:

  Q9NR19, Q6DKJ3

• Accession Number mRNA:

  NM_018677

• Chromosomal Location:

  20q11.22

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Glycolysis / Gluconeogenesis, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism

• Field of Research:

  Glycolysis / Gluconeogenesis, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  78.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ACSS2

• Species:

  Human

• Protein ID:

  NP_061147

• Overview:

  Recombinant protein of human acyl-CoA synthetase short-chain family member 2 (ACSS2), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/55902

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9NR19

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_018677

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_061147