NT5C (NM_014595) Human Recombinant Protein

• Background:

  This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2' (3') -dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]

• Synonyms:

  CdN; DNT; dNT-1; DNT1; HEL74; P5N2; PN-I; PN-II; UMPH2

• Gene ID:

  30833

• UniProt:

  Q8TCD5, V9HWF3

• Accession Number mRNA:

  NM_014595

• Chromosomal Location:

  17q25.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Metabolic pathways, Nicotinate and nicotinamide metabolism, Purine metabolism, Pyrimidine metabolism

• Field of Research:

  Metabolic pathways, Nicotinate and nicotinamide metabolism, Purine metabolism, Pyrimidine metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transcription Factors

• Molecular Weight:

  23.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  NT5C

• Species:

  Human

• Protein ID:

  NP_055410

• Overview:

  Recombinant protein of human 5', 3'-nucleotidase, cytosolic (NT5C)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/30833

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8TCD5

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_014595

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_055410