LY6H (NM_002347) Human Recombinant Protein

• Background:

  Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  NMLY6

• Gene ID:

  4062

• UniProt:

  O94772

• Accession Number mRNA:

  NM_002347

• Chromosomal Location:

  8q24.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  14.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  LY6H

• Species:

  Human

• Protein ID:

  NP_002338

• Overview:

  Recombinant protein of human lymphocyte antigen 6 complex, locus H (LY6H), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/4062

• Uniprot URL:

  https://www.uniprot.org/uniprot/O94772

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002347

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002338