ARTS1 (ERAP1) (NM_001040458) Human Recombinant Protein

• Background:

  The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]

• Synonyms:

  A-LAP; ALAP; APPILS; ARTS-1; ARTS1; ERAAP; ERAAP1; PILS-AP; PILSAP

• Gene ID:

  51752

• UniProt:

  Q9NZ08

• Accession Number mRNA:

  NM_001040458

• Chromosomal Location:

  5q15

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protease, Secreted Protein

• Molecular Weight:

  107.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ERAP1

• Species:

  Human

• Protein ID:

  NP_001035548

• Overview:

  Recombinant protein of human endoplasmic reticulum aminopeptidase 1 (ERAP1), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/51752

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9NZ08

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001040458

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001035548