Epithelial Stromal Interaction 1 (EPSTI1) (NM_001002264) Human Recombinant Protein

• Background:

  The protein encoded by this gene has been shown to promote tumor invasion and metastasis in some invasive cancer cells when overexpressed. Expression of this gene has been shown to be upregulated by direct binding of the Kruppel like factor 8 protein to promoter sequences. The translated protein interacts with the amino terminal region of the valosin containing protein gene product, resulting in the nuclear translocation of the nuclear factor kappa B subunit 1 gene product, and activation of target genes. Overexpression of this gene has been observed in some breast cancers and in some individuals with systemic lupus erythematosus (SLE) . [provided by RefSeq, Sep 2016]

• Synonyms:

  BRESI1

• Gene ID:

  94240

• UniProt:

  Q96J88

• Accession Number mRNA:

  NM_001002264

• Chromosomal Location:

  13q14.11

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transmembrane

• Molecular Weight:

  47.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  EPSTI1

• Species:

  Human

• Protein ID:

  NP_001002264

• Overview:

  Recombinant protein of human epithelial stromal interaction 1 (breast) (EPSTI1), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/94240

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q96J88

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001002264

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001002264