GBP5 (NM_052942) Human Recombinant Protein

• Background:

  This gene belongs to the TRAFAC class dynamin-like GTPase superfamily. The encoded protein acts as an activator of NLRP3 inflammasome assembly and has a role in innate immunity and inflammation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2017]

• Synonyms:

  GBP-5

• Gene ID:

  115362

• UniProt:

  Q96PP8

• Accession Number mRNA:

  NM_052942

• Chromosomal Location:

  1p22.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  66.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  GBP5

• Species:

  Human

• Protein ID:

  NP_443174

• Overview:

  Recombinant protein of human guanylate binding protein 5 (GBP5), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/115362

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q96PP8

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_052942

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_443174