PABP (PABPC1) (NM_002568) Human Recombinant Protein

• Background:

  This gene encodes a poly (A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly (A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly (A) promotes ribosome recruitment and translation initiation; it is also required for poly (A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010]

• Synonyms:

  PAB1; PABP; PABP1; PABPC2; PABPL1

• Gene ID:

  26986

• UniProt:

  P11940, A0A024R9C1

• Accession Number mRNA:

  NM_002568

• Chromosomal Location:

  8q22.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  70.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PABPC1

• Species:

  Human

• Protein ID:

  NP_002559

• Overview:

  Recombinant protein of human poly (A) binding protein, cytoplasmic 1 (PABPC1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/26986

• Uniprot URL:

  https://www.uniprot.org/uniprot/P11940

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002568

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002559