Aminopeptidase A (ENPEP) (NM_001977) Human Recombinant Protein

• Background:

  The ENPEP gene encodes glutamyl aminopeptidase, a type II integral membrane protein with an extracellular zinc-binding domain. This protein can upregulate blood pressure by cleaving the N-terminal aspartate from angiotensin II, and can regulate blood vessel formation and enhance tumorigenesis in some tissues. Along with ANPEP and DPP4, ENPEP was found to be a candidate co-receptor for the coronavirus SARS-CoV-2, which causes COVID-19. [provided by RefSeq, Apr 2020]

• Synonyms:

  APA; CD249; gp160

• Gene ID:

  2028

• UniProt:

  Q07075

• Accession Number mRNA:

  NM_001977

• Chromosomal Location:

  4q25

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Renin-angiotensin system

• Field of Research:

  Renin-angiotensin system

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, ES Cell Differentiation/IPS, Protease, Transmembrane

• Molecular Weight:

  109.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ENPEP

• Species:

  Human

• Protein ID:

  NP_001968

• Overview:

  Recombinant protein of human glutamyl aminopeptidase (aminopeptidase A) (ENPEP)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2028

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q07075

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001977

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001968