Apolipoprotein A V (APOA5) (NM_052968) Human Recombinant Protein

• Background:

  The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009]

• Synonyms:

  APOAV; RAP3

• Gene ID:

  116519

• UniProt:

  Q6Q788, A0A0B4RUS7

• Accession Number mRNA:

  NM_052968

• Chromosomal Location:

  11q23.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  PPAR signaling pathway

• Field of Research:

  PPAR signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Secreted Protein

• Molecular Weight:

  38.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  APOA5

• Species:

  Human

• Protein ID:

  NP_443200

• Overview:

  Recombinant protein of human apolipoprotein A-V (APOA5)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/116519

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q6Q788

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_052968

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_443200