IL36 beta (IL36B) (NM_173178) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta) . This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

• Synonyms:

  FIL1; FIL1- (ETA) ; FIL1H; FILI- (ETA) ; IL-1F8; IL-1H2; IL1-ETA; IL1F8; IL1H2

• Gene ID:

  27177

• UniProt:

  Q9NZH7

• Accession Number mRNA:

  NM_173178

• Chromosomal Location:

  2q14.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Secreted Protein

• Molecular Weight:

  17.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  IL36B

• Species:

  Human

• Protein ID:

  NP_775270

• Overview:

  Recombinant protein of human interleukin 1 family, member 8 (eta) (IL1F8), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/27177

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9NZH7

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_173178

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_775270