Ephrin A2 (EFNA2) (NM_001405) Human Recombinant Protein

• Background:

  This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008]

• Synonyms:

  ELF-1; EPLG6; HEK7-L; LERK-6; LERK6

• Gene ID:

  1943

• UniProt:

  O43921

• Accession Number mRNA:

  NM_001405

• Chromosomal Location:

  19p13.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Axon guidance

• Field of Research:

  Axon guidance

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  21.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  EFNA2

• Species:

  Human

• Protein ID:

  NP_001396

• Overview:

  Recombinant protein of human ephrin-A2 (EFNA2)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1943

• Uniprot URL:

  https://www.uniprot.org/uniprot/O43921

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001405

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001396