Tenascin C (TNC) (NM_002160) Human Recombinant Protein

• Background:

  This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, and neuronal regeneration. [provided by RefSeq, Jul 2011]

• Synonyms:

  150-225; DFNA56; GMEM; GP; HXB; JI; TN; TN-C

• Gene ID:

  3371

• UniProt:

  P24821, B4E1W8, Q4LE33

• Accession Number mRNA:

  NM_002160

• Chromosomal Location:

  9q33.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  ECM-receptor interaction, Focal adhesion

• Field of Research:

  ECM-receptor interaction, Focal adhesion

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane

• Molecular Weight:

  238.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TNC

• Species:

  Human

• Protein ID:

  NP_002151

• Overview:

  Recombinant protein of human tenascin C (TNC)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/3371

• Uniprot URL:

  https://www.uniprot.org/uniprot/P24821

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002160

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002151