OSBPL2 (NM_014835) Human Recombinant Protein

• Background:

  This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2014]

• Synonyms:

  DFNA67; DNFA67; ORP-2; ORP2

• Gene ID:

  9885

• UniProt:

  Q9H1P3

• Accession Number mRNA:

  NM_014835

• Chromosomal Location:

  20q13.33

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  53.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  OSBPL2

• Species:

  Human

• Protein ID:

  NP_055650

• Overview:

  Recombinant protein of human oxysterol binding protein-like 2 (OSBPL2), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9885

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9H1P3

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_014835

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_055650