14-3-3 beta (YWHAB) (NM_003404) Human Recombinant Protein

• Background:

  This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  GW128; HEL-S-1; HS1; KCIP-1; YWHAA

• Gene ID:

  7529

• UniProt:

  P31946, V9HWD6

• Accession Number mRNA:

  NM_003404

• Chromosomal Location:

  20q13.12

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis

• Field of Research:

  Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  27.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  YWHAB

• Species:

  Human

• Protein ID:

  NP_003395

• Overview:

  Recombinant protein of human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (YWHAB), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7529

• Uniprot URL:

  https://www.uniprot.org/uniprot/P31946

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003404

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003395