Peroxiredoxin 5 (PRDX5) (NM_181652) Human Recombinant Protein

• Background:

  This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein interacts with peroxisome receptor 1 and plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites is thought to result in transcript variants that use different in-frame translational start codons to generate isoforms that are targeted to the mitochondrion (isoform L) or peroxisome/cytoplasm (isoform S) . Multiple related pseudogenes have been defined for this gene. [provided by RefSeq, Nov 2017]

• Synonyms:

  ACR1; AOEB166; B166; HEL-S-55; PLP; PMP20; PRDX6; prx-V; PRXV; SBBI10

• Gene ID:

  25824

• UniProt:

  P30044

• Accession Number mRNA:

  NM_181652

• Chromosomal Location:

  11q13.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  12.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PRDX5

• Species:

  Human

• Protein ID:

  NP_857635

• Overview:

  Recombinant protein of human peroxiredoxin 5 (PRDX5), nuclear gene encoding mitochondrial protein, transcript variant 3

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/25824

• Uniprot URL:

  https://www.uniprot.org/uniprot/P30044

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_181652

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_857635