STK16 (NM_001008910) Human Recombinant Protein

• Background:

  Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  HPSK; KRCT; MPSK; PKL12; PSK; TSF1

• Gene ID:

  8576

• UniProt:

  O75716

• Accession Number mRNA:

  NM_001008910

• Chromosomal Location:

  2q35

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protein Kinase

• Molecular Weight:

  34.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  STK16

• Species:

  Human

• Protein ID:

  NP_001008910

• Overview:

  Recombinant protein of human serine/threonine kinase 16 (STK16), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8576

• Uniprot URL:

  https://www.uniprot.org/uniprot/O75716

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001008910

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001008910