MEF2C (NM_002397) Human Recombinant Protein

• Background:

  This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]

• Synonyms:

  C5DELq14.3; DEL5q14.3

• Gene ID:

  4208

• UniProt:

  Q06413, A0A024RAL7

• Accession Number mRNA:

  NM_002397

• Chromosomal Location:

  5q14.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  MAPK signaling pathway

• Field of Research:

  MAPK signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transcription Factors

• Molecular Weight:

  51 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MEF2C

• Species:

  Human

• Protein ID:

  NP_002388

• Overview:

  Recombinant protein of human myocyte enhancer factor 2C (MEF2C), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/4208

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q06413

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002397

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002388