UBE2W (NM_001001481) Human Recombinant Protein

• Background:

  This gene encodes a nuclear-localized ubiquitin-conjugating enzyme (E2) that, along with ubiquitin-activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA damage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

• Synonyms:

  UBC-16; UBC16

• Gene ID:

  55284

• UniProt:

  Q96B02, X6REH9

• Accession Number mRNA:

  NM_001001481

• Chromosomal Location:

  8q21.11

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Ubiquitin mediated proteolysis

• Field of Research:

  Ubiquitin mediated proteolysis

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transcription Factors

• Molecular Weight:

  18.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  UBE2W

• Species:

  Human

• Protein ID:

  NP_001001481

• Overview:

  Recombinant protein of human ubiquitin-conjugating enzyme E2W (putative) (UBE2W), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/55284

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q96B02

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001001481

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001001481