CES3 (NM_024922) Human Recombinant Protein

• Background:

  This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene is expressed in several tissues, particularly in colon, trachea and in brain, and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, but the biological validity and/or full-length nature of some variants have not been determined.[provided by RefSeq, Jun 2010]

• Synonyms:

  ES31

• Gene ID:

  23491

• UniProt:

  Q6UWW8

• Accession Number mRNA:

  NM_024922

• Chromosomal Location:

  16q22.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  62.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CES3

• Species:

  Human

• Protein ID:

  NP_079198

• Overview:

  Recombinant protein of human carboxylesterase 3 (CES3)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/23491

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q6UWW8

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_024922

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_079198