MAGEB1 (NM_177404) Human Recombinant Protein

• Background:

  This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region, and expressed in testis and in a significant fraction of tumors of various histological types. This gene and other MAGEB members are clustered on chromosome Xp22-p21. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene, however, the full length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]

• Synonyms:

  CT3.1; DAM10; MAGE-Xp; MAGEL1

• Gene ID:

  4112

• UniProt:

  P43366

• Accession Number mRNA:

  NM_177404

• Chromosomal Location:

  Xp21.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  38.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MAGEB1

• Species:

  Human

• Protein ID:

  NP_796379

• Overview:

  Recombinant protein of human melanoma antigen family B, 1 (MAGEB1), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/4112

• Uniprot URL:

  https://www.uniprot.org/uniprot/P43366

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_177404

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_796379