Heme oxygenase 2 (HMOX2) (NM_001127205) Human Recombinant Protein

• Background:

  Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]

• Synonyms:

  HO-2

• Gene ID:

  3163

• UniProt:

  P30519

• Accession Number mRNA:

  NM_001127205

• Chromosomal Location:

  16p13.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Porphyrin and chlorophyll metabolism

• Field of Research:

  Porphyrin and chlorophyll metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transmembrane

• Molecular Weight:

  35.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  HMOX2

• Species:

  Human

• Protein ID:

  NP_001120677

• Overview:

  Purified recombinant protein of Homo sapiens heme oxygenase (decycling) 2 (HMOX2), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/3163

• Uniprot URL:

  https://www.uniprot.org/uniprot/P30519

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001127205

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001120677