TRPC5 (NM_012471) Human Recombinant Protein

• Background:

  This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na (+) -H+ exchange regulatory factor (NHERF), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1) . [provided by RefSeq, May 2010]

• Synonyms:

  PPP1R159; TRP5

• Gene ID:

  7224

• UniProt:

  Q9UL62

• Accession Number mRNA:

  NM_012471

• Chromosomal Location:

  Xq23

• Expression System:

  E. coli

• Tag:

  N-His ABP

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, 8M Urea, pH8.0.

• Function:

  Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane

• Molecular Weight:

  28.0 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TRPC5

• Species:

  Human

• Protein ID:

  NP_036603

• Overview:

  Purified recombinant protein of Human transient receptor potential cation channel, subfamily C, member 5 (TRPC5), Pro812-His927, with N-terminal His-ABP tag, expressed in E.coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7224

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UL62

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_012471

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_036603