ROS1 (NM_002944) Human Recombinant Protein

• Background:

  This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008]

• Synonyms:

  C-ros-1; MCF3; ROS

• Gene ID:

  6098

• UniProt:

  P08922

• Accession Number mRNA:

  NM_002944

• Chromosomal Location:

  6q22.1

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, pH8.0, 8M Urea

• Function:

  Druggable Genome, Protein Kinase, Transmembrane

• Molecular Weight:

  27.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ROS1

• Species:

  Human

• Protein ID:

  NP_002935

• Overview:

  Purified recombinant protein of Human c-ros oncogene 1, receptor tyrosine kinase (ROS1), Trp1882-Val2125, with N-terminal His tag, expressed in E.coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/6098

• Uniprot URL:

  https://www.uniprot.org/uniprot/P08922

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002944

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002935