Apoc3 (NM_023114) Mouse Recombinant Protein

• Background:

  This gene encodes an apolipoprotein which is the major protein component of very-low-density lipoproteins (VLDL) and a minor component of high-density lipoproteins (HDL) . The encoded protein is thought to regulate the metabolism of triglyceride-rich lipoproteins and play a role in lipid storage and the mobilization of fat cells. This gene is clustered with three other apolipoprotein genes on chromosome 9 and is associated with coronary disease. Mice lacking this gene have lower levels of total cholesterol in the plasma. Mutations in the human genes causes hyperalphalipoproteinemia 2, a disorder of lipid metabolism which results in a favorable lipid profile (lower LDL-cholesterol, higher HDL-cholesterol and lower levels of serum triglycerides when fasting and after a meal) . Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

• Synonyms:

  Apo-CIII; apoC-III

• Gene ID:

  11814

• UniProt:

  P33622, A0A0R4J1N3

• Accession Number mRNA:

  NM_023114

• Chromosomal Location:

  9 25.36 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  11.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Apoc3

• Species:

  Mouse

• Protein ID:

  NP_075603

• Overview:

  Purified recombinant protein of Mouse apolipoprotein C-III (Apoc3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/11814

• Uniprot URL:

  https://www.uniprot.org/uniprot/P33622

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_023114

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_075603