Ppp1cc (NM_013636) Mouse Recombinant Protein

• Background:

  Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca (2+) /calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Dis2m1; PP-1G; PP1

• Gene ID:

  19047

• UniProt:

  P63087, Q6ZWM8

• Accession Number mRNA:

  NM_013636

• Chromosomal Location:

  5 F

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  37 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Ppp1cc

• Species:

  Mouse

• Protein ID:

  NP_038664

• Overview:

  Purified recombinant protein of Mouse protein phosphatase 1 catalytic subunit gamma (Ppp1cc), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/19047

• Uniprot URL:

  https://www.uniprot.org/uniprot/P63087

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_013636

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_038664