Dnmt3l (NM_019448) Mouse Recombinant Protein

• Background:

  CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein that is a catalytically inactive regulatory factor of DNA methyltransferases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

• Synonyms:

  D6Ertd14; D6Ertd14e; ecat; ecat7

• Gene ID:

  54427

• UniProt:

  Q9CWR8, A3EWM2

• Accession Number mRNA:

  NM_019448

• Chromosomal Location:

  10 39.72 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  48 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Dnmt3l

• Species:

  Mouse

• Protein ID:

  NP_062321

• Overview:

  Purified recombinant protein of Mouse DNA (cytosine-5-) -methyltransferase 3-like (Dnmt3l), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/54427

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9CWR8

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_019448

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_062321