Tti2 (NM_001112729) Mouse Recombinant Protein

• Background:

  Regulator of the DNA damage response (DDR) . Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC) . Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  MGC28346

• Gene ID:

  234138

• UniProt:

  Q8BGV4

• Accession Number mRNA:

  NM_001112729

• Chromosomal Location:

  8 A3

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  56.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Tti2

• Species:

  Mouse

• Overview:

  Purified recombinant protein of Mouse TELO2 interacting protein 2 (Tti2), transcript variant 1, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/234138

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8BGV4

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001112729