Il12rb1 (NM_008353) Mouse Recombinant Protein

• Background:

  Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  CD212; IL-12R[b]

• Gene ID:

  16161

• UniProt:

  Q60837

• Accession Number mRNA:

  NM_008353

• Chromosomal Location:

  8 34.21 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  82.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Il12rb1

• Species:

  Mouse

• Protein ID:

  NP_032379

• Overview:

  Purified recombinant protein of Mouse interleukin 12 receptor, beta 1 (Il12rb1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/16161

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q60837

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_008353

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_032379