C5ar1 (NM_001173550) Mouse Recombinant Protein

• Background:

  Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  C5aR; C5r1; Cd88; D7Msu1

• Gene ID:

  12273

• UniProt:

  P30993

• Accession Number mRNA:

  NM_001173550

• Chromosomal Location:

  7 8.77 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  39.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  C5ar1

• Species:

  Mouse

• Protein ID:

  NP_001167021

• Overview:

  Purified recombinant protein of Mouse complement component 5a receptor 1 (C5ar1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/12273

• Uniprot URL:

  https://www.uniprot.org/uniprot/P30993

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001173550

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001167021