Trim6 (NM_001013616) Mouse Recombinant Protein

• Background:

  E3 ubiquitin-protein ligase which ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells (PubMed:22328504) . Involved in the synthesis of unanchored K48-linked polyubiquitin chains which interact with and activate the serine/threonine kinase IKBKE, leading to phosphorylation of STAT1 and stimulation of an antiviral response (PubMed:24882218) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  C430046K18Rik; D7Ertd684e

• Gene ID:

  94088

• UniProt:

  Q8BGE7

• Accession Number mRNA:

  NM_001013616

• Chromosomal Location:

  7 55.55 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  56.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Trim6

• Species:

  Mouse

• Protein ID:

  NP_001013637

• Overview:

  Purified recombinant protein of Mouse tripartite motif-containing 6 (Trim6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/94088

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8BGE7

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001013616

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001013637