Il21 (NM_021782) Mouse Recombinant Protein

• Background:

  Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG (1) and IgG (3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity) . During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  IL-21

• Gene ID:

  60505

• UniProt:

  Q9ES17, Q5SUE2

• Accession Number mRNA:

  NM_021782

• Chromosomal Location:

  3 B

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  16.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Il21

• Species:

  Mouse

• Protein ID:

  NP_068554

• Overview:

  Purified recombinant protein of Mouse interleukin 21 (Il21), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/60505

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9ES17

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_021782

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_068554