Bmpr2 (NM_007561) Mouse Recombinant Protein

• Background:

  This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs) . The encoded protein is a type II receptor that binds extracellular BMPs and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important during embryonic development. Mutations in this gene can cause pulmonary hypertension. [provided by RefSeq, Mar 2013]

• Synonyms:

  2610024H22Rik; AL117858; AW546137; BB189135; BM; BMP; BMP-; BMP-2; BMPR-2; BMPR-II; BMPRII; BRK-3; Gm20272

• Gene ID:

  12168

• UniProt:

  O35607, Q3UG09, Q3UER5, Q3UU71

• Accession Number mRNA:

  NM_007561

• Chromosomal Location:

  1 C2

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  115.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Bmpr2

• Species:

  Mouse

• Protein ID:

  NP_031587

• Overview:

  Purified recombinant protein of Mouse bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/12168

• Uniprot URL:

  https://www.uniprot.org/uniprot/O35607

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_007561

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_031587