Bmpr1a (NM_009758) Mouse Recombinant Protein

• Background:

  On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction (PubMed:24098149) . Mediates induction of adipogenesis by GDF6 (PubMed:23527555) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  1110037I22Rik; ALK3; AU045487; Bmpr; BMPR-IA

• Gene ID:

  12166

• UniProt:

  P36895, Q53Z43

• Accession Number mRNA:

  NM_009758

• Chromosomal Location:

  14 20.81 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  60.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Bmpr1a

• Species:

  Mouse

• Protein ID:

  NP_033888

• Overview:

  Purified recombinant protein of Mouse bone morphogenetic protein receptor, type 1A (Bmpr1a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/12166

• Uniprot URL:

  https://www.uniprot.org/uniprot/P36895

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_009758

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_033888