KDM4D (NM_018039) Human Recombinant Protein

• Background:

  Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  JMJD2D

• Gene ID:

  55693

• UniProt:

  Q6B0I6

• Accession Number mRNA:

  NM_018039

• Chromosomal Location:

  11q21

• Expression System:

  E. coli

• Tag:

  N-GST and C-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, pH8.0, 8M Urea.

• Molecular Weight:

  86.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  KDM4D

• Species:

  Human

• Protein ID:

  NP_060509

• Overview:

  Purified recombinant protein of Human lysine (K) -specific demethylase 4D (KDM4D), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/55693

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q6B0I6

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_018039

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_060509