VDAC2 (NM_003375) Human Recombinant Protein

• Background:

  This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

• Synonyms:

  POR

• Gene ID:

  7417

• UniProt:

  P45880, A0A024QZT0

• Accession Number mRNA:

  NM_003375

• Chromosomal Location:

  10q22.2

• Expression System:

  E. coli

• Tag:

  N-GST and C-His

• Related Pathways:

  Calcium signaling pathway, Huntington's disease, Parkinson's disease

• Field of Research:

  Calcium signaling pathway, Huntington's disease, Parkinson's disease

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl

• Function:

  Druggable Genome, Ion Channels: Other

• Molecular Weight:

  59.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  VDAC2

• Species:

  Human

• Protein ID:

  NP_003366

• Overview:

  Purified recombinant protein of Human voltage-dependent anion channel 2 (VDAC2), nuclear gene encoding mitochondrial protein, transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7417

• Uniprot URL:

  https://www.uniprot.org/uniprot/P45880

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003375

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003366