CRM1/XPO1 Rabbit mAb (AMR12763N)

• Background:

  This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES) -dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015]

• Synonyms:

  CRM1; emb; exp1; XPO1

• Gene ID:

  7514

• UniProt:

  O14980

• Cellular Locus:

  Cajal body, Cytoplasm, Nucleus, nucleolus, nucleoplasm

• Dilution:

  WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

• Form:

  Liquid

• Buffer:

  Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

• Molecular Weight:

  Calculated MW: 110kDa Observed MW: 110KDa

• Storage Conditions:

  Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CRM1/XPO1 Rabbit mAb (APR24501N5) .

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7514

• Uniprot URL:

  https://www.uniprot.org/uniprot/O14980

• AA Sequence:

  Email for sequence